Lacritin, a Novel Human Tear Glycoprotein, Promotes Sustained Basal Tearing and Is Well Tolerated

摘要

Lacritin is a novel human tear glycoprotein that when added topically promotes tearing in normal New Zealand White rabbits. After a two-week treatment, lacritin stimulated basal tearing, and cyclosporine triggered mild to moderate corneal irritation and a temporary elevation in tearing.